D-Ribose
Ribose is a sugar component of ribonucleic acid. Ribose is found in the nucleotides. These are molecules that are contained as the smallest components of nucleic acid and together represent the smallest unit of information that enables the encoding of the genetic code in DNA and RNA. The human body can synthesize ribose itself from other simple sugars (= monosaccharides) via the so-called pentose phosphate cycle. Ribose also contributes to the energy supply of the muscle / muscle cells with ATP (= adenosine triphosphate). ATP is consumed by the muscle during exercise / training phases and must be synthesized again by the body after use. Ribose helps with this by being absorbed by the muscle cells and consumed during ATP formation.
Effects
Manufacturers promise a strong increase in strength in the form of rapid muscle growth and maximum ATP production. In addition, ribose is said to enable a shorter regeneration time. In cases of intensive training, ATP, the elementary driving energy of all muscular movements, as well as its pre- and degradation stages are significantly reduced. Even a regeneration time of two to three days does not reach the level of drive energy that existed before the training session. Parallels can be drawn here with a rechargeable battery: The battery uses itself up faster than the time it needs to be recharged afterwards.
Only when the drive energy has been restored can the muscle apparatus be supplied with metabolic energy again. Scientific studies have shown that ribose accelerates the process of renewed energy supply and thus reduces the regeneration time. Side effects No known side effects.
Optimal dosage
The dosages vary considerably in some cases. According to scientific studies, it is now assumed that a daily dose of approx. 4 g/d is sufficient to maintain the elementary drive energy in the form of ATP in the muscle at a performance level. Ribose contributes to the supply of ATP to the muscle cells, which ultimately provides the muscles with energy. This means that the initial regeneration time required by the body to recharge its "batteries" can be significantly reduced.
Safety and side effects
Ribose appears to be safe and harmless when taken orally for a short period of time or when administered intravenously by a doctor. Ribose can cause some side effects including diarrhea, stomach discomfort, nausea, headaches and low blood sugar levels.
Not enough is known about the safety and safety of long-term use of ribose.
Precautions and warnings
Pregnancy and lactation: Not enough is known about the safety of Ribose during pregnancy and lactation. For this reason, pregnant and breastfeeding women should avoid ribose to be on the safe side.
Diabetes: Ribose may lower blood sugar levels. If ribose is used in conjunction with diabetes medication that lowers blood sugar levels, it could cause an excessive drop in blood sugar levels. It is best to avoid ribose if you suffer from diabetes.
Low blood sugar (hypoglycemia): Ribose could lower blood sugar levels. If you already suffer from low blood sugar levels, you should not use ribose.
Operations: Because ribose may lower blood sugar levels, there are concerns that ribose may interfere with blood sugar control during and after surgery.
Interactions
Care should be taken when combining Ribose with the following medications:
Insulin and other diabetes medications
Ribose could lower blood sugar. Insulin and other diabetes medications are also used to lower blood sugar levels. Taking ribose in combination with the use of insulin and other diabetes medications could result in an excessive drop in blood glucose levels. For this reason, blood glucose levels should be carefully monitored. It is possible that the dosage of diabetes medication may need to be adjusted.
Alcohol
Alcohol could lower blood sugar levels. Ribose could also lower blood sugar levels. Taking ribose in combination with alcohol could result in an excessive drop in blood glucose levels.
Aspirin
Ribose could lower blood sugar levels. Large amounts of aspirin could also lower blood sugar levels. Taking ribose in combination with large amounts of aspirin could result in an excessive drop in blood sugar levels. However, this interaction is unlikely to be a major concern for most people who take aspirin in small amounts of 81 mg per day
Choline magnesium trisalicylate
Choline magnesium trisalicylate may lower blood sugar levels. Ribose could also lower blood sugar levels. Taking ribose in combination with choline magnesium trisalicylate could result in an excessive drop in blood glucose levels. However, it is not clear whether this interaction is a major cause for concern.
Salsalate
Large amounts of salsalate can lower blood sugar levels. Consuming salsalate in combination with ribose could result in an excessive drop in blood glucose levels.