Low selenium levels are associated with muscle weakness in older adults

Selenium plays a role in protein synthesis, maintaining muscle mass, immune function and neutralizing free radicals (highly reactive chemicals that naturally occur in the body and promote aging and disease). Many older people do not get enough selenium through their diet, which can contribute to muscle wasting (sarcopenia).
A study of nearly 1,000 older adults (65 years and older) living in Italy conducted by the John Hopkins School of Medicine found that low blood selenium levels are associated with muscle weakness. Grip strength, knee strength and hip strength were greatest in the subjects with the highest selenium levels. Low selenium levels contribute to reduced strength, muscle mass, balance and agility in older adults. Tap water and protein-rich foods such as meat contain selenium and it is also commonly added to multivitamin pills. Care should be taken when taking selenium-containing supplements, as excessive selenium intake can be toxic and even fatal.
(American Journal Clinical Nutrition, 86:347-352, 2007)