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Tryptophan

Tryptophan ist eine essentielle Aminosäure, die in Lebensmitteln reichlich vorhanden ist. Die Bildung und Freisetzung von Tryptophan hängt mit davon ab, ob ausreichend L-Tryptophan vorhanden ist.
Tryptophan ist als Baustein der Proteinsynthese und für den Leberstoffwechsel wichtig. Es kann in Niacin überführt werden und trägt so zu einem guten Niacin-Status in den Geweben sowie zur Biosynthese des Coenzyms Nikotinamid-Adenin-Dinukleotid (NAD) bei. Annähernd 60 mg Tryptophan sind äquivalent zu 1 mg Niacin. Entsprechend treten Niacinmängel erst bei einer tryptophanarmen Ernährung auf. Tryptophan wird außerdem für die Bildung von Tryptamin (biogenes Amin) benötigt, das den Blutdruck erhöht. Es trägt zur Bildung des beruhigend wirkenden Neurotransmitters Serotonin bei, das auf den Schlaf-Wach-Rhythmus ebenso wie auf Stimmungen und Schmerzempfinden einwirkt. Bekannt ist beispielsweise die schlaffördernde Wirkung von Milch als Schlaftrunk, die auf dem enthaltenen Tryptophan beruht.

Die Hauptlieferanten von Tryptophan
Tryptophan kommt in vielen Lebensmitteln vor. Besonders reich an dieser Aminosäure ist das Lactalbumin, der wasserlösliche Teil des Molkeproteins, das ebenfalls viel Tryptophan enthält. Tryptophan ist entsprechend in der Milch und in Milchprodukten reichlich enthalten. Diese Aminosäure wird durch den Kontakt mit Sauerstoff schnell abgebaut. Sie geht daher bei vielen Verarbeitungsprozessen in der Lebensmittelindustrie verloren bzw. wird in ihrem Anteil verringert.

Einige Tryptophan-reiche Lebensmittel enthalten in je 100 Gramm

Typische Gruppen für einen Mehrbedarf an Tryptophan

Sportler
eventuell bei Schlafstörungen und Depressionen

Wenn Tryptophan im Körper fehlt
Ein Mangel an Tryptophan kann zum Hartnup-Syndrom führen, bei dem Aminosäuren vermehrt ausgeschieden werden. Die Krankheit führt zu Pellagra-ähnlichen Symptomen (Lichtdermatosen durch Malabsorption von Tryptophan). Weiter können Hauterkrankungen, Störungen im Zentralen Nervensystem und Depressionen, abhängig vom Serotonin-Mangel, entstehen.

Kann man Tryptophan überdosieren oder gibt es Nebenwirkungen?
In den 80er Jahren entstand der Verdacht, dass die Gabe von Tryptophan mit dem eosinophilem Myalgie-Syndrom verbunden ist. In Untersuchungen bestätigte sich dieser Verdacht nicht. Die betreffenden Fälle beruhten vermutlich auf Verunreinigungen eines einzelnen Tryptophan-Präparates bei der Herstellung. Seit 1996 ist Tryptophan in Deutschland daher wieder als Arzneimittel zugelassen. Werden bei Depressionen MAO-Hemmer eingenommen, sollte Tryptophan nicht angewendet werden. Sportler sollten hohe Einnahmen von Tryptophan, im Bereich von über 3 Gramm täglich, vermeiden. Zu hohe Dosen können das Blutbild verändern und zu Muskelschmerzen und Müdigkeit führen.

Der tägliche Bedarf an Tryptophan
Der tägliche Bedarf an Tryptophan wird mit 250 mg angegeben.

- Gigas admin -

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The Gigas Sports Ltd. Website serves solely as a source of information about the products offered. All of our products are considered as dietary supplements and not as medication. The usage of any of our products takes place at your own risk. None of our products should be used for treatment, cure, prevention or diagnosis of a medical condition. We do not give medical advice. Please consult a medical doctor before using any of our products. This is especially important, if you are currently treated because of an existing medical condition or if you take any medication or hormone preparations. Please read all instructions and product information carefully and do not exceed the stated dosage. If you have any questions concerning the usage or the action of a dietary supplement consult your healthcare professional or nutritionist. Please discontinue the usage and contact your medical doctor if any adverse reactions occur. All information about a product originates from the manufacturer, the product label or the specialized press. Store all nutritional supplements out of the range of children. We take no liability for any impairment of your health or any other damage. We are not liable wrong information or changes in product Ingredients. Gigas Sports Ltd. is not liable for promises or directions made by the manufacturer of a product.

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Tryptophan

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Tryptophan